报告人：Prof. Xinguang Zhu, CAS-MPG Partner Institute for Computational Biology, SIBS, CAS
报告人：Prof. Xueping Zhou
201710.13【PSC Frontier Seminar Series】:Calcium signaling is required for ABA mediated transcriptional adaptation to abiotic stresses报告时间：2017-10-14
【PSC Frontier Seminar Series】:Calcium signaling is required for ABA mediated transcriptional adaptation to abiotic stresses2017-10-13
Title:Calcium signaling is required for ABA mediated transcriptional adaptation to abiotic stresses
Speaker:Prof.Jörg Kudla, Institut für Biologie und Biotechnologie der Pflanzen, Westfälische Wilhelms-Universität Münster, Schlossplatz 7/8, 48149 Münster, Germany.
Day/Date: October 14th, 2017 (Saturday)
Host PI: Prof. Jiankang Zhu
Venue: PSC Auditorium
Calcium and ABA function as central signals in responses to stresses like drought, cold and salinity. Nevertheless, the interrelations between the formation and function of both messengers remained largely enigmatic. Here, I show that the occurrence of calcium signals is pivotal to establish plant stress responses. Accordingly, these calcium signatures are essential and sufficient for inducing ABA accumulation. Calcineurin B-like proteins (CBLs) upon interaction with specific CIPK protein kinases phosphorylate and activate ABA responsive transcription factors. Reconstituting complete calcium and ABA signaling pathways in human cell lines and plant protoplasts, established calcium signaling via specific CBL/CIPK complexes as required and sufficient for ABF2 activation. Together with the phosphorylation analyses of other transcription factors, these results indicate that calcium triggered, CBL/CIPK mediated phosphorylation of transcription factors represents a widespread mechanism to ensure specificity and effectiveness of stress adaptation. I will discuss how this mechanism allows for integration, fine tuning and termination of hormonal and calcium signaling on the level of gene transcription.