PSC Frontier Seminar Series
Speaker: Prof. Yi Li, School of Life Sciences, State Key Laboratory of Protein and Plant Gene Research Peking University
Time: 14:00 pm
Day/Date: September 20th, 2018 (Thursday)
Host PI: Prof. Rosa Lozano-Duran
Venue: PSC Auditorium
Viral infections induce a series of rice responses, these responses including host antiviral RNAi, plant hormone and many other pathways. RNAi, the evolutionarily conserved mechanism of antiviral defense which is well studied in model plant and other eukaryotes, is poorly understood in economically important crops. Rice encodes 19 AGOs, AGO18 is a member of a novel sub-clade of AGOs from monocotyledons, which is highly induced by infections of evolutionary different viruses. Loss-of-function ago18 mutation abolishes, whereas over-expression of AGO18 increases antiviral activity. Further research found that AGO18 sequesters certain miRNAs under viral infection conditions. These miRNAs may directly involved in antiviral defense. The detailed molecular mechanism was elucidated. Viral infections also modify host hormone pathway either synthesis or signaling, these modification either benefits viral infection or suppresses viral infection.
The Seminar will be delivered in English*