学术活动
学术活动

植物科学前沿系列讲座

2018-10-25

 
PSC Frontier Seminar Series
Title: The Companion of Cellulose Synthase 1 confers salt tolerance through a Tau-like mechanism in plants
Speaker: Prof. Staffan Persson, University of Melbourne (Australia)
Time: 10:00 am
Day/Date: October 25th, 2018 (Thursday)
Host PI: Prof. Alberto Macho
Venue: No.1 meeting room
 
Abstract: 
Plant biomass is largely comprised of polysaccharide-based cell walls, of which cellulose is the main constituent. Understanding how cellulose synthesis is regulated is therefore of immense importance to agriculture and plant biology. The COMPANION OF CELLULOSE SYNTHASE1 (CC1) sustains cellulose synthesis during salt stress by regulating microtubule assembly and cellulose synthase localization in Arabidopsis. We show that CC1 binds microtubules through conserved hydrophobic regions that are connected by flexible linkers. Mutations of two key residues in one of these hydrophobic CC1 regions impaired the protein’s microtubule-binding ability and impaired microtubule-guided cellulose synthesis, which reduced the plant’s ability to grow on salt-containing media. Structural assessments, binding behaviour and dynamics of CC1 in the context of microtubules indicate that it functions analogously to the prominent microtubule-associated and neuropathology-related protein Tau. Hence, CC1 sustains microtubule-based cellulose synthesis during salt stress via a Tau-like mechanism in plants.
 
The seminar will be delivered in English.