PSC Frontier Seminar series
Title: A glimpse of lncRNA function and regulation in transcription, stem cell and development
Speaker: Prof. Xiaohua Shen, Tsinghua University
Time: 10:00 am
Day/Date: December 21st, 2018 (Friday)
Host PI: Prof. Jian-Kang Zhu
Venue: PSC Auditorium
Much of the developmental complexity of higher eukaryotes is thought to arise from gene regulation rather than from an increase in the number of protein-coding genes. RNA represents a hidden layer of regulatory information in complex organisms. Long noncoding RNAs (lncRNAs) have been increasingly recognized as important regulators of transcription and chromatin structure. However, the functionality of vast majorities of lncRNAs is unknown. Identifying functional lncRNAs and revealing their regulatory mechanisms represent major challenges in understanding genome complexity and RNA-mediated gene regulation. I will discuss recent progresses we have made in understanding lncRNA’s function and regulation in contexts of chromatin, stem cell and development.
The seminar will be delivered in English.