PSC Frontier Seminar series
Title: Molecular genetic basis of autoimmunity in Arabidopsis
Speaker: Prof. Jian Hua, Cornell University, Ithaca, NY
Time: 10:00 am
Day/Date: Feb 22nd, 2019 (Friday)
Host PI: Prof. Yang Zhao
Venue: No.1 meeting room
Autoimmunity is the activation of immune responses in the absence of pathogen invasion, leading to constitutive defense responses and compromised plant growth and even plant death. It occurs in some inter- or intra-hybrid plants or results from perturbation of various cellular processes. Prior studies have revealed that the activation of plant immune receptor NLR genes is the cause of a large number of cases of autoimmunity. How NLR genes are repressed during non-pathogen invasion conditions and how they are activated under induced conditions are not well understood. We are addressing these questions by studying the autoimmunity of the bon1 mutant resulting from the upregulation of a NLR gene SNC1 in Arabidopsis. I will present data indicating an important role of calcium signaling and chromatin modification in NLR gene regulation. The tight control of NLR expression is likely critical for the fine tuning of plant immunity as well as the balance between growth and immunity.
The seminar will be delivered in English.