学术活动
学术活动

植物科学前沿系列讲座

2019-02-26

 

PSC Frontier Seminar series

 

Title 1: Genetic analysis of SA signaling in Arabidopsis (3:00 PM - 4:00 PM)

Speaker: Prof. Yuelin Zhang, University of British Columbia, Vancouver, BC, Canada

Day/Date: Feb 27th, 2019 (Wednesday)

Host PI: Prof. Jian-Kang Zhu

Venue: PSC Auditorium

 

Abstract:

Salicylic acid (SA) is a key plant defense hormone with critical roles in different aspects of plant immunity. My lab studies how SA biosynthesis is regulated during plant defense and how SA is perceived. Analysis of Arabidopsis mutants revealed complex regulation of pathogen-induced SA biosynthesis and perception. NPR1 function as a transcriptional activator and SA promotes its transcriptional activation activity. On the other hand, NPR3 and NPR4 act as transcriptional repressors and SA inhibits their transcriptional repression activities to promote the expression of SA-responsive genes. Our evidence supports that both NPR1 and NPR3/NPR4 are bona fide SA receptors, but play opposite roles in transcriptional regulation of SA-induced defense gene expression.

 

 

Title 2: Regulation of plant immunity by proteasome mediated protein degradation (4:00 PM - 5:00 PM)

Speaker: Prof. Xin Li, University of British Columbia, Vancouver, BC, Canada

Day/Date: Feb 27th, 2019 (Wednesday)

Host PI: Prof. Jian-Kang Zhu

Venue: PSC Auditorium

 

Abstract:

Nucleotide-binding leucine-rich repeat (NLR) immune receptors play crucial roles in pathogen recognition and defense activation in animals and plants. The immune responses mediated by NLR proteins are tightly regulated so that the host can effectively respond to pathogen attack without experiencing autoimmunity. However, the mechanisms underlying this regulation are not fully understood. Using the snc1 mutant as an autoimmune model, our lab has identified both positive and negative regulators of NLR-mediated immunity. In particular, we have identified an NLR degradation pathway including N-terminal acetylation, ubiquitination and proteasome mediated degradation. These findings extend our knowledge on the interplay among NLRs and how their homeostasis is regulated through the ubiquitination pathway.

The seminar will be delivered in English.