PSC Frontier Seminar series
Title: Plant innate immunity mediated by cell wall derived signals
Speaker: Prof. Antonio Molina, Universidad Politecnica de Madrid and Centro de Biotecnologia y Genomica de Plantas (CBGP, UPM-INIA), Spain
Time: 14:00 pm
Day/Date: May 27th, 2019 (Monday)
Host: Prof. Rosa Lozano-Duran / Prof. Alberto Macho
Venue: PSC auditorium
Plant innate immune system can be activated by microbe-associated molecular patterns (MAMPs), but also by damage-associated molecular patterns (DAMPs) that trigger immune responses upon recognition by plant Pattern Recognition Receptors (PRRs). DAMPs are signaling molecules released from host cellular structures (i.e. plant cell walls) upon pathogen infection or wounding. Despite the hypothesized important role of DAMPs in plant-pathogen interactions, a very limited number of DAMPs are well characterized. Typical examples of carbohydrate-based DAMP/MAMPs are oligogalacturonides, b-glucans and chitin. Cell wall extracts from Arabidopsis thaliana cell wall mutants showing altered susceptibility/resistance to several pathogens were chemically and chromatographically fractionated and these wall fractions were tested for their capacity to activate the plant innate immune system. Notably, several wall fractions were found to trigger immune responses and those showing the highest activity were further characterized. These analyses pointed to a role of pentose oligosaccharides triggering immune responses. Further research revealed that b-1,4-xylooligosaccharides of specific degrees of polymerization carrying arabinose decorations are sensed as DAMPs by Arabidopsis. The molecular mechanisms of these and other potential novel cell wall derived DAMPs in the regulation of plant immunity are being characterized and will be presented. The potential differences/similarities between DAMP and MAMP-triggered immune response will be discussed.
The seminar will be delivered in English.