学术活动
导师介绍

何跃辉
研究员,博士生导师


Email: yhhe@sibs.ac.cn
Phone:(86) 21- 57078221

研究方向:

植物发育表观遗传学; 植物开花时间(花期)及根系发育调节基因的分子与表观遗传调控机理

代表性论文:

Wang, Y., Gu, X., Yuan, W., Schmitz, R. and He, Y. (2014) Photoperiodic control of the floral transition through a distinct Polycomb repressive complex. Developmental Cell, 28(6):727-36

Gu, X., Xu, T., He, Y. (2014) A histone H3 lysine-27 methyltransferase complex represses lateral root formation in Arabidopsis thaliana. Molecular Plant, 7(6): 977-88

Gu, X., Wang, Y. &He, Y. (2013) Photoperiodic regulation of flowering time through periodic histone deacetylation of the florigen gene FT. PLoS Biology, 11: e1001649

Gu, X., Le, C., Wang, Yi., Li, Z., Jiang, D., Wang, Yu. &He, Y. (2013) Arabidopsis FLC clade members form flowering-repressor complexes coordinating responses to endogenous and environmental cues. Nature Communications, 4(1947): 1-10

Xu, Y., Wang, Y., Stroud, H., Gu, X., Sun, B., Gan, E., Ng, K., Jacobsen, S., He, Y.* and Ito, T.* (*Co-correspondence authors). (2013) A matrix protein silences transposons and repeats through interaction with Retinoblastoma-associated proteins.Current Biology, 23: 345-350

He, Y. (2012) Chromatin regulation of flowering. Trends in Plant Science, 17:
556-627

Gu, X., Jiang, D., Yang, W., Jacob, Y., Michaels, D. and He, Y. (2011) Arabidopsis homologs of Retinoblastoma-Associated Protein 46/48 associate with a histone deacetylase to act redundantly in chromatin silencing. PLoS Genetics, 7(11): e1002366

Jiang, D., Kong, N., Gu, X., Li, Z. and He, Y. (2011) Arabidopsis COMPASS-like complexes mediate histone H3 lysine-4 trimethylation to control the floral transition and plant development. PLoS Genetics, 7(3): e1001330

Yang, W., Jiang, D., Jiang, J. and He Y. (2010) A plant-specific histone H3 lysine 4 demethylase represses the floral transition in Arabidopsis. Plant Journal 62: 663-73

Jiang, D., Gu, X. and He, Y. (2009) Establishment of the winter-annual growth habit via FRIGIDA-mediated histone methylation at FLOWERING LOCUS C in Arabidopsis. Plant Cell, 21:1733-46

Gu, X., Jiang, D., Wang, Y., Bachmair, A. and He, Y. (2008) Repression of the floral transition via histone H2B monoubiquitination. Plant Journal, 57:522-33

Jiang, D., Yang, W., He, Y. (Correspond. author) and Amasino, R. (2007) Arabidopsis relatives of the human Lysine-Specific Demethylase 1 repress the expression of FWA and FLOWERING LOCUS C and thus promote the floral transition. Plant Cell, 19:2975-87

Sung, S.*, He, Y.* (*Co-first author), Eshoo, T., Tamada, Y., Johnson, L., Nakahigashi, K., Goto, K., Jacobsen, S., and Amasino, R. (2006) Epigenetic maintenance of the vernalized state in Arabidopsis thaliana requires LIKE HETEROCHROMATIN PROTEIN 1. Nature Genetics, 38: 706-10

He, Y., Doyle, M. and Amasino, R. (2004) PAF1 complex-mediated histone methylation of FLOWERING LOCUS C chromatin is required for the vernalization-responsive, winter-annual habit in Arabidopsis. Genes and Development, 18:2774-84

He, Y., Michaels, S. and Amasino, R. (2003) Regulation of flowering time by histone acetylation in Arabidopsis. Science, 302:1751-54

Xie, M.*, He, Y.*(*Co-first author) and Gan, S. (2001) Bidirectionalization of polar promoters in plants. Nature Biotechnology, 19:677-9