学术活动
研究组
 
           

郎曌博
研究员,博士生导师


电话:86 (21)-57078250
Email: zblang@sibs.ac.cn

代表性论文


1.Qian, W., Miki, D., Lei, M., Zhu, X., Zhang, H., Liu, Y., Li, Y., Lang, Z., Wang, J., Tang, K., Liu R., Zhu J.-K. (2014). Regulation of active DNA demethylation by an α-crystallin domain protein in Arabidopsis. Molecular Cell 55 (3), 361–371.

2. Zhang, H., Tang, K., Qian, W., Duan, C.-G., Wang, B., Zhang, H., Wang, P., Zhu, X., Lang, Z., Yang, Y., Zhu J.-K. (2014). An Rrp6-like protein positively regulates noncoding RNA levels and DNA methylation in Arabidopsis. Molecular Cell 54 (3), 418–430.

3.Zhang, H., Tang, K., Wang, B., Duan, C.-G., Lang, Z., and Zhu, J.-K. (2014). Protocol: a beginner's guide to the analysis of RNA-directed DNA methylation in plants. Plant Methods 10, 18.

4.Lang, Z., Lei, M., Wang, X., Tang, K., Miki, D., Zhang, H., Mangrauthia, S.K., Liu, W., Nie, W., Ma, G., Yan J., Duan C., Hsu C., Wang C., Tan W., Gong Z., Zhu J.-K. (2015). The Methyl-CpG-Binding Protein MBD7 Facilitates Active DNA Demethylation to Limit DNA Hyper-Methylation and Transcriptional Gene Silencing. Molecular Cell 57 (6), 971–983.

5.Wan Y., Tang K., Zhang D., Xie S., Zhu X., Wang Z., Lang Z.* (2015) Transcriptome-wide high-throughput deep m6A-seq reveals unique differential m6A methylation patterns between three organs in Arabidopsis thaliana. Genome Biology 16 (1), 1-26 (*Corresponding author)

6.Lang, Z., and Zhu, J.-K. (2015). OST1 phosphorylates ICE1 to enhance plant cold tolerance. Science China Life Science 58 (3), 317-8.

7.Zhan, X., Zhu, J.-K., and Lang, Z.* (2015). Increasing Freezing Tolerance: Kinase Regulation of ICE1. Developmental Cell 32 (3), 257–258. (*Corresponding author)

8.Lang, Z., and Zuo, J. (2015). Say “NO” to ABA signaling in guard cells by S-nitrosylation of OST1. Science China Life Science 58 (3), 313-4.

9.Wang P., Zhu J.-K., Lang Z. * (2015) Nitric oxide suppresses the inhibitory effect of abscisic acid on seed germination by S-nitrosylation of SnRK2 proteins. Plant Signaling & Behavior 10 (6) p.e1031939. (*Corresponding author)

10.Wang, C., Dong, X., Jin, D., Zhao, Y., Xie, S., Li, X., He, X., Lang, Z., Lai, J., Zhu, J.-K., Gong Z. (2015). Methyl-CpG-Binding Domain Protein MBD7 Is Required for Active DNA Demethylation in Arabidopsis. Plant Physiology 167 (3), 905–914.

11.Zhao, C., Lang, Z., Zhu, J.-K. (2015) Cold responsive gene transcription becomes more complex. Trends in Plant Science 20 (8), 466-468.

12.Duan, C.-G., Zhang, H., Tang, K., Zhu, X., Qian, W., Hou, Y.-J., Wang, B., Lang, Z., Zhao, Y., Wang, X., Wang P., Zhou J., Liang G., Liu N., Wang C., Zhu J.-K. (2015). Specific but interdependent functions for Arabidopsis AGO4 and AGO6 in RNA-directed DNA methylation. The EMBO Journal 34 (5), 581–592.

13.Zhan X., Yang L., Wang D., Zhu J.-K, Lang Z.*, (2016) De novo assembly and analysis of the transcriptome of Ocimum americanum var. pilosum under cold stress. BMC Genomics, 17(1): 209, DOI 10.1186/s12864-016-2507-7. (*Corresponding author).

14.Lang Z. *, and Gong Z. *, (2016) Novel roles of an RNaseIII enzyme. Nature Plants, 2:16021. (*Corresponding author)

15.Zhang Q.*, Wang D.*, Lang Z.*, He L., Yang. L, Zeng L., Li Y., Zhao C., Huang H., Zhang H., Zhang H., Zhu J.-K. (2016) The RNA-directed DNA methylation pathway mediates wide spread DNA methylation interactions in Arabidopsis hybrids. Proceedings of the National Academy of Science 113 (29), E4248-56 (*equal contribution).

16.Lang Z., Xie S., Zhu J-K. (2016) The 1001 Arabidopsis DNA Methylomes: An Important Resource for Studying Natural Genetic, Epigenetic, and Phenotypic Variation. Trends in Plant Science DOI: 10.1016/j.tplants.2016.09.001

17.Tang K.*, Lang Z.*, #, Heng Zhang, Zhu J.-K. (2016) The DNA demethylase ROS1 targets genomic regions with distinct chromatin modifications. Nature Plants (Accepted, *equal contribution, #corresponding author).